Evaluate the Effect of Implant-Supported Prostheses on the Bioavailability of Nutrients: A Systematic Review and Meta-Analysis


  • Parsa Mehrinejad, Behnoosh Jalalian, Farasat Moradi, Mohammad Dehghan


Background and aim:The aim of this study was to evaluate the Effect of Implant-Supported Prostheses on the Bioavailability of Nutrients by Systematic Review and Meta-Analysis.

Method: Databases of PubMed, Scopus, Web of Science, EBSCO and Embase were searched for systematic literature between 2010 to August 2021.  For Data extraction, two reviewers blind and independently extracted data from abstract and full text of studies that included.95% confidence interval for mean differences with fixed effect model and Inverse-variancemethod were calculated. To deal with potential heterogeneity, random effects were used and I2 showed heterogeneity. Meta-analysis was performed using Stata/MP v.16 software (The fastest version of Stata).

Result: In the initial review, duplicate studies were eliminated and abstracts of 326 studies were reviewed, the full text of 121 studies was reviewed by two authors, finally, nine studies were selected.  Meta-analysis showed that serum folate concentration was not different after 12 months in the intervention and control groups. No significant differences were observed between groups for nutrient residues after 12 months. Significant differences were observed for albumin in the control and intervention groups; similarly, vitamin B12 levels also increased.

Conclusion: Based on the findings of the present meta-analysis, the use of dental implant-supported prostheses has no significant effect on the bioavailability of several nutrients in patients with complete or partiallyedentulous.